Not only the brain, but the whole person...just ask me if I don't get enough sleep...my brain and I have that discussion too often I feel...(grin)...BD

Ever get a little testy after a bad night's sleep? Scientists may now know why. A new study finds that a lack of sleep causes the brain's emotional centers to dramatically overreact to negative experiences. A shutdown of the prefrontal lobe -- a brain region that normally keeps emotions under control -- is the reason for heightened emotional response in sleep-deprived people, said the researchers from Harvard Medical School and the University of California, Berkeley.

Sleepless Nights Make for Grumpier Brains - Forbes.com

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