Study comparing current anti-depressants to a pill form of marijuana..and states that THC (contains the same active ingredient found in marijuana) could be a fruitful target for new anti-anxiety drugs...BD 

Right now, about half of all people who take medicine for an anxiety disorder don't get much help from it. And doctors have no definitive way to predict who will, and who won't, benefit from each anti anxiety prescription they write.

In a placebo controlled design, they made the findings after giving the volunteers delta 9 tetrahydrocannabinol (THC), the active ingredient in marijuana, and exposing them to photographs of emotional faces, which served as signals of social communication. The image study results, which showed that THC reduces the response to threat in a brain region called the amygdala, allowed the researchers to zero in on an area of the brain that might serve as a good target for new anti-anxiety drugs.

The researchers chose fMRI because it allows them to see in real time which areas of the brain are most active while a volunteer is performing a certain task for example, viewing a picture of a human face that is expressing anger or fear, or performing a decision-making exercise.  The cannabis study used THC, and a placebo caplet that looked exactly like the THC caplet. The researchers found that when the marijuana users received THC, their brain's response to "threatening" faces was less than it was when they received a placebo.  But there were no differences between THC and placebo in the areas of the brain that process non-emotional visual signals or govern body movement suggesting that THC had a specific effect on a specific brain region and on a specific task of processing fear.

Serotonin has long been known to be involved in depression and anxiety, and indeed most modern antidepressant and anti-anxiety drugs (such as SSRIs) work on this transporter.

High Anxiety?

1 comments :

  1. Most of the drug addicts suffer from lot of disorders. These drug disorders are nausea, headache, vomiting, skin rashes, weight loss, and several other disorders. The extent of disorders depends upon the dose of the drugs.

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