Good article well worth reading...and it points out some of the areas where we already have personalized medicine in place today...health care providers will need to get up to speed...more genetic counselors will be needed...physicians who have not tracked this information will be put on the spot...do we start incorporating this information in to medical records...software developers put on the spot...design the processes for the physicians...and last but not least, reimbursement for prevention needs to be accelerated...BD
Medscape: What are the most important developments in genomics that might affect clinical practice?
In terms of diagnostics, we are already in a position with some heritable conditions where it's possible to determine who is at risk even before the disease has appeared, perhaps most dramatically in circumstances like the BRCA1 and BRCA2 genes.
You will see more of those kinds of diagnostic tests to assess what are the appropriate next steps to take for cancer, particularly now that we have The Cancer Genome Atlas project. Then there's pharmacogenomics, the effort to try to make better predictions about getting the right drug at the right dose for the right person.
For example, the commonly used drug warfarin, for blood clotting, now includes on the FDA label a suggestion that physicians be aware that genetic testing can help choose the proper maintenance dose of a drug that has a very narrow therapeutic window. Potentially in the next 2 or 3 years, that suggestion will become a recommendation based upon data that are being accumulated right now.
Genomic Research and Personalized Medicine: An Expert Interview
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