Ok put me at the head of the line for this.  I have gone through and have dental implants so I know the drill here and what makes this even more fascinating is the fact that the tooth can be grown inside the empty tooth socket, this is amazing.  I have done several interviews with Cook Medical, one of the companies who is in the regenerative medicine business and we talked about how the scaffolds are built.  image

Regenerative Medicine and How it Works – Interview with Cook Biotech (Medical)

There’s a clinical trial in Australia that started with women being able to regrow their own breast too with stem cells.  It’s amazing how fast and powerful this technology is today. 

Regenerative Medicine: Clinical Trial To Begin with Women in Australia Using Stem Cells To ReGrow Breasts – Has Been Successful with Pigs

I am guessing though you need good tooth stem cells?  Maybe that’s a dumb question but I am curious as to how this would work with individuals like myself that were dealt a bad deck of “tooth genes”.  BD 

Conventional dental implants are typically screwed into the patient’s jaw bone, require visits to several types of clinicians, take two to six months to heal, and are still subject to failure. Not exactly an ideal solution to missing teeth. A professor of dental medicine at Columbia University Medical Center, however, has devised a technique wherein implants could be grown in the empty tooth socket, right inside the patient’s mouth.

Dr. Jeremy Mao started with a tooth-shaped scaffold made of microchannelled natural materials, infused with a growth factor. In an animal-model study, he placed that structure in a recipient’s empty tooth socket, then caused their stem cells to home (migrate) onto the scaffold. It resulted not only in the growth of a new tooth-like structure, but also in the regeneration of periodontal ligaments and the formation of new alveolar bone.

Dental implants could be grown inside patients' mouths

Related Reading:

Regenerative Medicine – Material and Cell Based Regeneration of the Human Body
Biomagic "pixie dust" regrows man's lopped-off finger

Dr. Oz Visits a regenerative medicine lab in Wake Forest

The Heart Can Repair Itself – Stem Cells Help Speed up the Healing

6 comments :

  1. Regenerative dentistry! It sounds cool and interesting. Definitely a significant improvement in the history of medical field. Thanks for sharing an informative post. Keep posting more and do stay in touch.

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  2. I am very interested in talking to anyone who has had an implant done at bradley dean in plano, tx that failed after the crown was placed. Please contact markah_1999@yahoo dot com. I spent $22K + with bradley dean in plano, tx and they still want more $$$$$ to fix the problem. I went broke paying up front for what was supposed to be a permanent solution. It lasted maybe 6 months...

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  3. Very informative post you have here.

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  4. Dental Implant placement usually takes two surgical appointments:

    - During the first surgical appointment the implant site is prepared to receive the implant following strict aseptic procedures. The selected size of the implant is placed in the prepared site. The gum tissue is sutured over the implant. The implant takes 4- 6 months to fuse with the bone.

    - During the second surgical appointment the implant is uncovered and the appropriate post is attached to which the replacement tooth is anchored. An impression of the post is taken and sent to the lab for the fabrication of the implant crown. During this time a temporary crown is placed. Once the final crown is back it is cemented with permanent cement.

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  5. Dental implants are replacement of tooth roots. Dental Implants provide a strong foundation for removable replacement teeth that are made to match your natural teeth. When a tooth is lost the specialized bony process that houses the tooth begins to resorb due to lack of stimulation. This causes a decrease in width and height of the bone in the area the tooth is lost. Neighboring teeth and opposing teeth begin to move into the space. This causes food lodgment, subsequent decay, gum disease and abnormal forces being transmitted to teeth leading to fracture of cusps which may necessitate root canal treatment or extraction. Loss of teeth can also cause the cheek and lips to collapse giving an aged look.

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