As the article states, when you bring in additional genetics information, the disease gets a lot more complicated...like everything in life...more information to manage for the right solution...BD 

Merck is using a new technique that it believes could turn genetic information into new drugs, a key bottleneck for the pharmaceutical industry as it struggles to invent new medicines.
The techniques, described in the current version of the journal Nature, are an example of a technique biologists have been touting for years: treating all 25,000 genes as a complicated network. Each gene is seen not as a single switch, but as part of a vast and complex circuit board. Scientists call this "systems biology."
"There's a heck of a lot that's going on between the change in DNA and the onset of the disease," says Eric Schadt, the Merck researcher.

This is telling us the disease is a lot more complex than we imagined." He says his new technique, which could identify changes in this genetic circuit board that would stop obesity without causing harm, is "a path forward for how to leverage the amazing rate of discovery in genomics."

All Connected - Forbes.com

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